Publications

Optimizing Microemulsion Process Parameters for Operational Stability

Presentor: Raiche, A.; Womack, A; Staas, J.
Presented at:American Association of Pharmaceutical Scientists. San Diego, CA, November 13

Tailoring of Poly(lactide-co-glycolide) to Control Properties

Presentor: Middleton, J.
Presented at:BioInterface, San Mateo, CA, October 30-31

Novel Long-Acting Parenterals-Microparticles and Injectable Solid Implants

Presentor: Tice, T.R.
Presented at:26th Annual Symposium of Toxicologic Pathology. Rio Grande, Puerto Rico, June 10-14

Design for Peptide Delivery

Presentor: Tice, T.R.
Presented at:6th Annual European Drug Delivery Partnerships. Berlin, Germany, May 15-16

Tailoring of Poly(lactide-co-glycolide) to Control Properties

Presentor:Middleton, J.
Presented at:Society of Biomaterials, Pittsburg, PA, April 18-21

Efficacy of Rifabutin-loaded Microspheres for Treatment of Mycobacterium Avium-Infected Macrophages and Mice

Presentor:Barrow, E.; Barrow, W.; Quenelle, D.; Westbrook, L.; Winchester, G.; Staas, J.
Presented at:Drug Delivery, Volume 14, Issue 3, March 2007, Pages 119-127

Design for Peptide Delivery

Presentor: Tice, T.R.; Woehr, T.
Presented at:11th Annual Drug Delivery Partnerships. Las Vegas, NV, January 22-24

2006 Articles and Presentations

Selecting the Right Formulation Technology

Presentor: Tice, T.R.
Presented at:33rd Annual Meeting and Exposition of the Controlled Release Society. Vienna, Austria, July 25

Scale-up: Development to Commercialization

Presentor: Hudson, M.
Presented at:33rd Annual Meeting and Exposition of the Controlled Release Society. Vienna, Austria, July 25

Scale-up: Development to Commercialization

Presentor: Staas, J.K., Bruce W. Hudson, Arthur J. Tipton, Thomas R. Tice, Brenda H. Perkins, Jennifer M. Shaw
Presented at:33rd Annual Meeting and Exposition of the Controlled Release Society. Vienna, Austria, July 25

Preparation of Biodegradable Nanoparticles by a Scalable Emulsion-Based Process

Presentor: Markland, P., Gary A. Winchester
Presented at:33rd Annual Meeting and Exposition of the Controlled Release Society. Vienna, Austria, July 25

Drug Delivery with Injectable Solid Implants

Presentor:Tice, T.R.
Presented at:The 10^th Annual Drug Delivery Partnerships Conference. Phoenix, AZ. 2006 January 23-27

Drug Delivery with Long-Acting Parenterals

Presentor:Tice, T.R.
Presented at:SMi 5^th Annual Conference on Controlled Release: Recent Trends and Future Technologies.  London, UK. 2006 February  13-14

2005 Articles and Presentations

Delivery from Injectable Microparticles and Injectable Solid Implants

Presentor: Tice, T.R.
Presented at:Drug Delivery Technologies & Deal-Making Summit. New Brunswick, NJ. 2005 September 26-28

Scale-up to manufacturing of pharmaceutical processes

Presentor: Hudson, M.
Presented at: The 32nd Annual Meeting & Exposition of the Controlled Release Society Meeting; Miami Beach, FL, 2005 June 18-22

Sustained release of methadone from biodegradable DL-PLG microspheres

Presentors: Markland, P.; Warden, G.
Presented at: 32nd Annual Meeting & Exposition of the Controlled Release Society Meeting, Miami Beach, FL, 2005 June 18-22

In vitro - in vivo correlation of release kinetics: a method for a peptide-containing implant

Presentors: Hudson, B.W.; Perkins, B.H.; Shaw, J.M.; Staas, J.K.
Presented at: 32nd Annual Meeting & Exposition of the Controlled Release Society Meeting, Miami Beach, FL, 2005 June 18-22

Sustained release formulation of Nalmefene for treatment of alcoholism

Presentors: Perkins, B.H.; Markland, P.
Presented at: 32nd Annual Meeting & Exposition of the Controlled Release Society Meeting, Miami Beach, FL, 2005 June 18-22

Development of a CTL vaccine for Her-2/neu using peptide-microspheres and adjuvants

Authors: Mossman, S.P.; Evans, L.S.; Fang, H.; Staas, J.; Tice, T.; Raychaudhuri, S.; Grabstein, K. and Johnson, M.E.
Publication: Vaccine 23: 3545-3554

Enhancing value with depot formulations

Presentor: Tice, T.R.
Presented at: The 9th Annual Drug Delivery Partnerships Conference. San Diego, CA. 2005 January 24-26

2004 Articles and Presentations

Depot microparticle formulations for the delivery of pharmaceuticals

Presentor: Tice, T.R.
Presented at: Advances in Controlled Release and Drug Delivery Technologies Short Course at the Center for Microencapsulation & Drug Delivery, College Station, TX. 2004 October 27-28

Depot formulations...performance tests for injectable microparticles and implants

Presentor: Tice, T.R.
Presented at: Presented at US Pharmacopeial First Annual Scientific Meeting, Iselin, NJ. 2004 September 27-29

Delivery of proteins and peptides with depot formulations

Presentor: Tice, T.R.
Presented at: The 8th Annual Drug Delivery Partnerships Conference. Beverly Hills, CA. 2004 January 27-29

Delivering with depot formulations

Author: Tice, T.R.
Publication: Drug Delivery Technology. 4(1): 44-47

Sustained release characteristics of rifampin-loaded microsphere formulations in nonhuman primates

Authors: Quenelle, D.C.; Winchester, G.A., Staas, J.K.; Hoskins, D.E.; Barrow, W.W.; Barrow, E.W.
Publication: Drug Delivery 11: 1-8

2003 Articles and Presentations

Sucrose acetate isobutyrate for parenteral delivery

Author: Tipton, Arthur J.
Publication: Chapter 57 in Modified-Release Drug Delivery Technology, 2003

Delivery of cromolyn sodium from biodegradable coaxial implants

Presentors: Meador, Stacey, Gibson, John, Thorsen, Arthur, Wright, Jerry, Chan Tai Wah, Yum, Su Il, Lee, Min, Tipton, Arthur J.
Presented at: The AAPS Annual Meeting and Exposition, 2003, October 26-30, Salt Lake City

Local analgesia using controlled release of bupivacaine from a novel SAIB-based organogel system

Presentors: Burton, Kevin, Atkins, Griet, Verity, Neil, Martin,, Thomas, Beuchler, Nancy, Kim, Suzy, Tipton, Arthur J.
Presented at: The AAPS Annual Meeting and Exposition, 2003, October 26-30, Salt Lake City

Local controlled release of bupivacaine from a novel SAIB-Based organogel system

Presentors: Burton, Kevin, Smith, Forest, Atkins, Griet, Verity, Neil, Middleton, John, Tipton, Arthur J.
Presented at: The AAPS Annual Meeting and Exposition, 2003, October 26-30, Salt Lake City

Oral sustained release for 12-24 Hours from SABER-filled softgel capsules

Presentors: Tipton, Arthur J., Midleton, J.M., McDuffie, C.D., Billingsley, S., Williams, J., Fisher, D., Fu, K., Halladay, S., Miller, V., Dang. W., Hutchison, K., Savello,. D.
Presented at: The AAPS Annual Meeting and Exposition, 2003, October 26-30, Salt Lake City

Peptide and protein delivery from the SABER system

Presentor: Tipton, Arthur, J. (Invited lecture)
Presented at: The AAPS National Biotechnology Conference, June 24-26, 2002, San Diego

2002 Articles and Presentations

The science and technology behind parenteral depot/implants

Presentor: P. Markland
Presented at: Current Trends in Parenteral Drug Delivery Symposium at the 2002 AAPS Pharmaceutics and Drug Delivery (PDD) Conference, Arlington, Virginia, April 22-24, 2002

Biodegradable polymers as drug carriers

Authors: Markland, P. and Yang, V.C.
Publication: The Encyclopedia of Pharmaceutical Technology, 2nd Edition; Swarbrick, J. and Boylan, J.C. (Eds.); Marcel Dekker, Inc., New York, May, 2002

Poly(glutamic acid) poly(ethylene glycol) hydrogels prepared by photo-induced polymerization: synthesis, characterization, and preliminary release studies of protein drugs

Authors: Zhang, Y., Zhang, Y., Markland, P., and Yang, V.C.
Publication: Journal of Biomedical Materials Research, 62(1), 14-21 (2002)

The fate of biodegradable microspheres injected into rat brain

Authors: Nicholas, A.P.; McInnis, Carey; Gupta, K.B.; Snow, W.W.; Love, D.F.; Mason, D.W.; Ferrell, T.M.; Staas, J.K.; Tice, T.R.
Publication: Neuroscience Letters. 323: 85-88 (2002)

2001 Articles and Presentations

Treatment of tuberculosis using a combination of sustained-release rifampin-loaded microspheres and oral dosing with isoniazid

Authors: Quenelle, D.C.; Winchester, G.A.; Staas, J.K.; Barrow, E.L.; Barrow, W.W.
Publication: Antimicrobial Agents and Chemotherapy, Vol. 45, Number 6, pp. 1637-1644

Gels

Presentor: Tipton, A.J. (invited lecturer)
Presented at: AAPS Workshop (co-sponsored with the FDA and USP) on Assuring Quality and Performance of Sustained and Controlled Release Parenterals, April 19-20, 2001, Washington, DC

2000 Articles and Presentations

Drug delivery from a controlled release aerosol: effects of formulation variables

Presentors: Carraway, K.M., Meador, S.K., Sullivan, S.A., Gibson, J.W., Tipton, A.J.
Presented at: AAPS Annual Meeting and Exposition, 2000, October 29 - November 2, Indianapolis, Indiana

Zero-Order, 30-Day Release of Analgesics from Coaxial Implants

Presentors: Meador, S., Jefferson, R., Maturi, H., Carraway, M., Gibson, J., Tipton, A.
Presented at:28th International Symposium of The Controlled Release Society, 2001, June 23-27, San Diego, California

Evaluation of the SABERTM Delivery System for Sustained Release of Growth Hormone B Formulation Design and In Vivo Assessment

Presentors: Okumu, F., Daugherty, A., Dao, L., Felder, P., Brooks, D., Sane, S., Sullivan, S.A., Tipton, A.J., Cleland, J.
Presented at:28th International Symposium of The Controlled Release Society, 2001, June 23-27, San Diego, California

Local Delivery from a Novel Biodegradable In Situ Delivery System

Presentors: Tipton, Arthur J., Sullivan, Stacey A., Carraway, K. Michelle, Smith, Dawn A., Gibson, John W.
Presented at:Sixth World Biomaterials Congress, Kamuela, Hawaii, May 15-20, 2000

SABERTM Provides Burst Free Release of Growth Hormone from PLGA Microspheres.

Presentors: Okumu, F.W., Darling, S., Dao, L.N., Fielder, P.J., Sullivan, S.A., Tipton, A.J., Cleland, J.L.
Presented at:Millennial World Congress of Pharmaceutical Sciences, San Francisco, California, April, 16-20, 2000

Extended Release of Human Growth Hormone Suspended in SABERTM Formulation Design and In Vitro Assessment

Presentors:Darling, S., Okumu, F.W., Sullivan, S.A., Tipton, A.J., Cleland, J.L.
Presented at:Millennial World Congress of Pharmaceutical Sciences, San Francisco, California, April 16-20, 2000

Sustained Release Injectable Products, In: In Situ Gelling Formulations

Presentors:Tipton, Arthur J., Dunn, Richard L. (edited by Judy Senior, Michael Radomsky)
Presented at:Interpharm Press, Inc. Buffalo Grove, IL, 2000

Depot Delivery of Proteins in the New Millennium: From Microspheres to Injectable Gels

Presentors:Cleland, Jeffrey L., Johnson, OluFumni L., Darling, Susan, Tipton, Arthur J., Zentner, G
Presented at:6th European Symposium on Controlled Drug Delivery, Noordwijk Aan Zee, April 12, 2000, The Netherlands

Local Delivery from a Novel Biodegradable In Situ Delivery System

Presentors:Tipton, Arthur J., Sullivan, Stacey A., Carraway, K. Michelle, Smith, Dawn A., Gibson, John W.
Presented at:Sixth World Biomaterials Congress, May 15-20, 2000, Kamuela, Hawaii

Drug release from a novel controlled release aerosol based on sucrose acetate isobutyrate

Presentors: Carraway, K. Michelle, Sullivan, Stacey A., Meador, Stacey K., Williams, Julie C., Gibson, John W., Tipton, A.
Presented at:AAPS Midwest Regional Meeting. 2000, May 22, Chicago, Illinois

Effect of Gamma Irradiation on Leuprolide Acetate Release from Polylactide Implants

Presentors: Gibson, J.W,. Meador, S.K., Tanglertpaibul, J., Bhardwaj, R., Ingallinera, T.S., Tipton, A.J.
Presented at:27th Symposium on Controlled Release of Bioactive Materials, July 9-13, 2000, Paris, France

Incorporation of polymer microparticles into Sucrose Acetate Isobutyrate reduces burst and extends release

Presentors: Sullivan, S.A., Meador, S.K., Carraway, K.M., Tipton, A.J., Gibson, J.W.
Presented at:27th Symposium on Controlled Release of Bioactive Materials, July 7-13, 2000, Paris, France

Evaluation of SABERTM as a local delivery system for RhVEGF formulation design and In Vitro assessment

Presentors: Okumu, F.W., Daugherty, A., Sullivan, S.A., Tipton, A.J., Cleland, J.L.
Presented at:27th Symposium on Controlled Release of Bioactive Materials, July 9-13, 2000, Paris, France

In Situ gelling systems to delivery peptides and proteins

Presentors: Tipton, Arthur (invited lecture)
Presented at:5th International Drug Delivery Technologies and Deal-Making Conference, July 26-28, 2000. Princeton, NJ

Drug delivery from a controlled release aerosol: effects of formulation variables

Presentors: Carraway, K.M., Meador, S.K., Sullivan, S.A., Gibson, J.W., Tipton, A.J.
Presented at:AAPS Annual Meeting and Exposition, October 29 - November 2, 2000, Indianapolis, Indiana

Long-term stability of Poly(DL-lactide) and Poly(DL-lactide-co-glycolide) under different storage conditions

Presentors: Todd Williams, Patricia Kines, Craig Martin, and John Middleton.
Presented at:Sixth World Biomaterials Congress, 2000, May 15-20, Kamuela, Hawaii

Synthetic Biodegradable Polymers as Orthopedic Devices

Presentors: Middleton, John C., Tipton, Arthur J.
Presented at:Biomaterials, 2000, 21, 2335-2346

Synthetic Biodegradable Polymers as Orthopedic Devices

Presentors: John C. Middleton and Arthur J. Tipton
Presented at:Biomaterials, accepted for publication in 2000

Effects of Formulation variables on controlled release of paclitaxel and other chemotherapeutic agents from a novel delivery system

Presentors: Gibson, J.W., Sullivan, S.A., Carraway, K.M., Tipton, A.J.
Presented at:AAPS Annual Meeting and Exposition, 1999, November 14-18, New Orleans, Louisiana

Oral controlled release of antiretrovirals using the SABER delivery system incorporated into soft gelatin capsules

Presentors: Sullivan, S.A.; Gibson, J.W.; Tipton, A.J.; Carraway, K.M.
Presented at:AAPS Annual Meeting and Exposition, 1999, November 14-18, New Orleans, Louisiana

Sustained release of lysozyme from the SABER delivery system

Presentors: Sullivan, S.A., Meador, S.K., Carraway, K.M., Williams, J.C., Gibson, J.W., Tipton, A.J.
Presented at:AAPS Annual Meeting and Exposition, 1999, November 14-18, New Orleans, Louisiana

1999 Articles and Presentations

Combined Systemic and Mucosal Immunization with Microsphere-Encapsulated Inactivated Simian Immunodeficiency Virus Elicits Serum, Vaginal, and Tracheal Antibody Responses in Female Rhesus Macaques.

Presentors: Israel, Z.R.; Ghettie, A.; Ishizaka, S.T.; Mishkin, E.M.; Staas, J.K.; Gilley, R.M.; Montefiori, D.; Marx, P.A.; Eldridge, J.H.
Presented at:Aids Research and Human Retrovirus, Vol. 15, Number 12, pp. 1121-1136

Abstract: Exploring new drug delivery platform - synthesis, characterization, and preliminary protein release of a pH-responsive hydrogel.

Presentors: Yang, Z., Markland, P., Zhang, Y., Amidon, G.L., Yang, V.C.
Presented at:Pharmaceutical Research, 1999 AAPS Annual Meeting

Efficacy Evaluations of microencapsulated rifampicin in mycobacterium tuberculosis-infected mice

Presentors: Quenelle, D.C.; Staas, J.K.; Winchester, G.A.; Barrow, E.L.W.; Barrow, W.W.
Presented at:Antimicrobial Agents and Chemotherapy 43: 1144-1151

Induction of mucosal antibody responses by microsphere-encapsulated formalin-inactivated simian immunodefiency Virus in a male urethral challenge model.

Presentors: Ishizaka, S.T.; Israel, Z.R.; Gettie, A.; Mishkin, E.M.; Staas, J.K.; Gilley, R.M.; Dailey, P.J.; Montefiori, D.C.; Marx, P.A.; Eldridge, J. H.
Presented at:Vaccine 17: 2817-2825

A pH- and ionic strength-responsive polypeptide hydrogel: Synthesis, characterization, and preliminary protein release studies

Presentors: Markland, P., Zhang, Y., Amidon, G.L., and Yang, V.C.
Presented at:Journal of Biomedical Materials Research, 47(4), 595-602

Biodegradable delivery systems for Estradiol: comparison between poly(DL-lactide) microspheres and the SABER delivery system.

Presentors: Johnson, C.A., Thompson, Jr., D.L., Sullivan, S.A., Gibson, J.W., Tipton, A.J., Simon, B.W., Burns, P.J.
Presented at:26th International Meeting of The Controlled Release Society, 1999, June 20-25, Boston, MA

Technical and business strategies to commercialize peptide and protein depot formulations

Presentors: Tice, T.R.
Presented at:Drug Delivery Symposium 1999. Berkeley, CA; 1999 June 15-18

New Delivery: Extension of Existing Products.

Presentors: Tipton, A.J. (Invited Lecture)
Presented at:AAPS Eastern Regional Meeting, June 10-11, 1999,Parsippany, New Jersey

Modified polypeptides containing -benzyl glutamic acid as drug delivery platforms

Presentors: Markland, P., Amidon, G.L. and Yang, V.C.
Presented at:International Journal of Pharmaceutics, 178, 183-192

The Effect of Peg End Groups on the Degradation of a 75/25 Poly(DL-lactide-co-glycolide)

Presentors: John C. Middleton and Julie C. Yarbrough.
Presented at:23rd Annual Meeting of the Society for Biomaterials Meeting, 1999, April 28 - May 2, Providence, Rhode Island

Technical and business strategies to commercialize peptide and protein depot formulations

Presentors: Tice, T.R.
Presented at:IBC's 3rd Annual Conference on Drug Delivery Systems. Washington, DC. 1999 May 24-25

In vitro and in vivo evaluation of a novel in situ-forming parenteral delivery system

Presentors: Gibson, J.W., Sullivan, S.A., Burns, P.J., Tipton, A.J.
Presented at:Poster at Recent Advances in Drug Delivery Systems, February 22-25, 1999, Salt Lake City, Utah

1998 Articles and Presentations

Use of microsphere technology for targeted delivery of rifampin to mycobacterium tuberculosis-infected macrophages

Authors: Barrow, L.W.; Winchester, G.A.; Staas, J.K.; Quenelle, D.C.; Barrow, W.W.
Publication:Antimicrobial Agents and Chemotherapy 42: 2682-2689

Synthesis and characterization of a pH-sensitive polypeptide hydrogel for drug delivery applications

Presentors: Markland, P.
Presented at:Pharmacia-Upjohn Walter F. Enz Awards Symposium, Brook Lodge, Augusta, Michigan. October 19, 1998

Abstract: Release of macromolecular drugs from a pH-sensitive polypeptide hydrogel containing poly(glutamic acid) and poly(ethylene glycol),

Authors: Markland, P., Zhang, Y., Amidon, G.L., and Yang, V.C.
Publication:Pharmaceutical Research

Developing mucosal-induced immunity with mucosal vaccines

Presentors: Tice, T.R.
Presented at:2nd Annual Capture Your Share of the Vaccine Market. Washington, DC; 1998 June 22-23

Poly(lactide-co-glycolide) biodegradable microspheres for the time release of peptides, proteins and vaccines

Presentors: Tice, T.R.
Presented at:1998 Conference on Pharmaceutical Science and Technology in conjunction with the 28th Annual Meeting of the Fine Particle Society. Dallas, TX; 1998 April 3

Synthetic Biodegradable Polymers as Medical Devices.

Authors: John C. Middleton and Arthur J. Tipton.
Publication:Medical Plastics and Biomaterials, 1998, March/April, 31-38

Long-Term Stability of Biodegradable Polymers

Presentors: C.T. Williams, J.C. Middleton, K.R. Sims, R.P. Swaim, D.R. Whitfield, and J.C. Yarbrough.
Presented at:17th Southern Biomedical Engineering Conference, 1998, February 6-8, San Antonio, Texas

Getting to the heart of growth factor delivery

Authors: Tice, T; Staas, J.
Publication:Nature Biotech. 16: 134

Drug delivery from in situ formed depot systems

Presentors: Tipton, A.J. (invited lecture)
Presented at:33rd Annual AAPS Pharmaceutical Technologies Section Arden House Conference, January 18-23, Harriman, New York

Synthetic Biodegradable Polymers as Medical Devices

Authors: Middleton, J.C. and Tipton, A.J.
Publication:Medical Plastics and Biomaterials, 1998, March/April, 31-38

Evaluation of the SABER™ delivery system for the controlled release of the GnRH analog deslorelin acetate for advancing ovulation in mares: effect of formulation and dose

Presentors: Squires, E.L., Fleury, J.J., Betschart, R., Gibson, J.W., Sullivan, S.A., Tipton, A.J., Burns, P.J.
Presented at:25th International Meeting of The Controlled Release Society, 1998, June 21-26, Las Vegas, Nevada

Evaluation of the SABER™ delivery system for the controlled release of the GnRH analog deslorelin acetate for advancing ovulation in mares: effect of gamma radiation

Presentors: Burns, P.J., Betschart, R., Fleury, J.J., Squires, E.L., Nett, T.M., Gibson, J.W., Sullivan, S.A., and Tipton, A.J.
Presented at:25th International Meeting of The Controlled Release Society, 1998, June 21-26, Las Vegas, Nevada

Comparison of in vitro and in vivo release of progesterone and estradiol from the SABER™ delivery system

Presentors: Sullivan,S.A., Burns, P.J., Gibson, J.W., Tipton, A.J.
Presented at:25th International Meeting of The Controlled Release Society, 1998, June 21-26, Las Vegas, Nevada

Sustained release of orally administered active using SABERTM delivery system incorporated in soft gelatin capsules

Presentors: Sullivan, S.A., Yarbrough, J.C., Fengl, R.W., Tipton, A.J., and Gibson J.W.
Presented at:25th International Meeting of The Controlled Release Society, 1998, June 21-26, Las Vegas, Nevada

Sustained release of Bupivacaine from the SABER delivery system

Presentors: Sullivan, S.A., Gibson, J.W., Tipton, A.J.
Presented at:AAPS Annual Meeting and Exposition, 1998, November 15-19, San Francisco, California

Use of microsphere technology for targeted delivery of rifampin to mycobacterium tuberculosis-infected macrophages

Presentors: Barrow, L.W.; Winchester, G.A.; Staas, J.K.; Quenelle, D.C.; Barrow, W.W.
Presented at:Antimicrobial Agents and Chemotherapy 42: 2682-2689

Induction of protective immune responses against Venezuelan equine encephalitis (VEE) virus aerosol challenge with microencapsulated VEE virus vaccine

Presentors: Greenway, T.E.; Eldridge, J.H.; Ludwig G.; Staas, J.K.; Smith, J.F.; Gilley, R.M.; Michalek, S.M.
Presented at:Vaccine 16: 1314-1323

Developing mucosal-induced immunity with mucosal vaccines

Presentor: Tice, T.R.
Presented at:2nd Annual Capture Your Share of the Vaccine Market. Washington, DC; 1998 June 22-23

Poly(lactide-co-glycolide) biodegradable microspheres for the time release of peptides, proteins and vaccines

Presentor: Tice, T.R.
Presented at:1998 Conference on Pharmaceutical Science and Technology in conjunction with the 28th Annual Meeting of the Fine Particle Society. Dallas, TX; 1998 April 3

1997 Articles and Presentations

Pharmacodynamic evaluation of the Saber delivery system for the controlled release of GnRH analogue deslorelin acetate for advancing ovulation in cyclic mares

Presentors: Burns, P., Thompson, D., Donadue, F., Kincald, L., Leise, B., Gibson, J., Swaim, R., Tipton, A.
Presented at:24th International Meeting of The Controlled Release Society, 1997, June 16-19, Stockholm, Sweden

Evaluation of the Saber delivery system for the release of GnRH analog deslorelin acetate for advancing ovulation in the mare

Presentors: Donadue, F.J., Thompson, D.L., Burns, P.J., Tipton, A.J., Gibson, J.W., Swaim, R.P., Kincald, L.A., Leise, B.S.
Presented at:15th Annual Meeting of the Equine Nutrition and Physiology Society Meeting, 1997, May 29-31, Fort Worth, Texas

The Melt Viscosity of Polyglycolic Acid as a Function of Shear Rate, Moisture, and Inherent Viscosity

Presentors: J.C. Middleton, C.T. Williams, and R.P. Swaim.
Presented at:22nd Annual Meeting of the Society for Biomaterials, 1997, April 30-May 4, New Orleans, Louisiana

Delivery of Taxol and other antineoplastics agents from a novel system based on Sucrose Acetate Isobutyrate.

Authors: Sullivan, S.A., Gilley, R.M., Gibson, J.W., Tipton, A.J.
Publication:Pharm. Res., 1997, 14(11), 291

Synthesis of a novel class of pH-responsive biocompatible hydrogels for drug delivery applications

Presentors: Markland, P.
Presented at:1997 Pharmaceutics Seminar Series, College of Pharmacy, The University of Michigan, Ann Arbor, Michigan. November 19, 1997

Properties influencing modified poly(amino acids) as drug delivery platforms for model hydrophilic drugs

Presentors: Markland, P.
Presented at:29th Annual Pharmaceutics Graduate Student Research Meeting (PGSRM), Iowa City, Iowa. June 19-21, 1997

Abstract: Synthesis and characterization of novel poly(amino acid) pH-responsive hydrogels

Presentors: Markland, P., Nguyen, N.A., Miles, A.M., Yang, V.C., and Amidon, G.L.
Presented at:Pharmaceutical Research, 14(11), S-292. 1997 AAPS Annual Meeting

Poly(lactide-co-glycolide) biodegradable microspheres and implants for the time release of peptides, proteins and nucleic acids

Presentors: Tice, T.R.
Presented at:International Business Communications Third International Conference on Advances in the Effective Delivery of Proteins, Peptides and Nucleic Acids. Coronado, CA; 1997 December 17-18

Design and Options for Developing Injectable Microspheres

Presentors: Tice, T.R.
Presented at:1997 Colorado Biopharmaceutical Delivery Conference. Breckenridge, CO; 1997 July 24-

In Vitro Characterization and Dissolution

Presentors: Tice, T.R.
Presented at:Presented at Land O' Lakes Conference. Lake Delton, WI; 1997 June 2-6

Delivery of anti-cancer-agents with microparticulates.

Presentors: Tice, T.R. Ferrell, T.M., Perkins, B.H., Mason, D.W., Love, D.H., Staas, J.K., Ohno, H., Imamori, K., Kasai, S., Ono, K., Okada, M., Suzuki, M., Ishigaki, K.
Presented at:American Association of Pharmaceutical Scientists - Midwest Regional Meeting. Chicago, IL; 1997 May 19

1996 Articles and Presentations

Abstract: Modified poly(amides) as drug delivery matrices: Effects of polymer hydrophobicity and structure on drug release,

Presentors: Markland, P., Amidon, G.L. and Yang, V.C.
Presented at:Pharmaceutical Research, 13(9), S-294. 1996 AAPS Annual Meeting

Antibody-directed enzymes for site-specific prodrug therapy

Presentors: Markland, P.
Presented at:1996 Medicinal Chemistry Seminar Series, College of Pharmacy, The University of Michigan, Ann Arbor, Michigan. February 8, 1996

Design, Preparation and Characterization of biodegradable poly(lactide-co-glycolide) microsphere formulations

Presentors: Tice, T.R.
Presented at:International Business Communications Second International Conference on Advances in the Effective Delivery of Proteins, Peptides and Nucleic Acids. Coronado, CA; 1996 December 12-13

Site-directed delivery of pharmaceuticals and vaccines

Presentors: Tice, T.R.
Presented at:Controlled Release Society's Conference entitled "Advances in Controlled Delivery." Baltimore, MD; 1996 August 19-20

A novel parenteral delivery system

Authors: Smith, D.A., Tipton, A.J.
Publication:Pharm. Res. 1996, 13(9), 300

1995 Articles and Presentations

Controlled release of heparin from vascular grafts over a 55 day period

Presentors: Espinal, E., Bulgrin, J., Chapman, M., Abbott, A., Schmidt, S., Tipton, A.
Presented at:American College of Surgeons Meeting, 1995, March 22-24, Akron, Ohio

Adjuvanticity and protective immunity elicited by Bordetella pertussis antigens encapsulated in poly(DL-lactide-co-glycolide) microspheres

Authors: Shahin, R.; Leef, M.; Edlridge, J.; Hudson; M.; Gilley, R.
Publication:Infect. Immun. 63: 1195-1200

Site-directed delivery of pharmaceuticals and vaccines

Presentors: Tice, T.R.
Presented at:Strategies for Effective Delivery of Proteins and Peptides; International Business Communications Symposium. Coronado, CA; 1995 September 28-29

Carrier-mediated antiviral therapy

Authors: Kende, M.; Tice, T.R.; Yan, C.
Publication:Drug Targeting Delivery 124 (6): 147-165

Enhancement of protective immune response to Venezuelen equine encephalitis (VEE) virus with microencapsulated vaccine

Authors: Greenway, T.E.; Eldridge, J.H.; Ludwig, G.; Staas, J.K.; Gilley, R.M.; Michalek, S.M.
Publication:Vaccine 13: 1411-1420

1994 Articles and Presentations

Influence of Injection Rate on Tensile Strength and Molecular Weight of Molded Poly(L-Lactide)Test Pieces

Presentors: D.N. Ellis and A.J. Tipton.
Presented at:Annual Meeting of the Society for Biomaterials, 1994, April 5-9, Boston, Massachusetts